Station 19 and Station 23 each attempt to celebrate Thanksgiving following the fallout from the neighborhood explosion. The firefighters come together to cook, toast to loved ones they have lost, and celebrate the families they have become.

A deadly face-off leads to a life-threatening moment; Catherine and Sam seek help for his parents.

Bill's latest discovery is put in jeopardy, even as trouble brews with the human aliens; Catherine must decide where her loyalties lie.

Inside the Wall, Tim – imprisoned and tortured on the Duke's orders – is convinced by his cellmate Jean-Pierre to write letters calling for revolution. They are rescued by Cherie and her fellow rebels, and prepare to overthrow the Duke. Tim and Cherie spend a passionate night together, and copies of Tim's letters spread throughout the Wall, drawing people to their cause; Cherie urges Tim to lead them. As the Duke addresses a congregation, his sheriff spots Tim in the crowd and attacks, killing Jean-Pierre. Tim unites the oppressed inhabitants of the Wall in an open rebellion. The Duke floods the lower levels, drowning countless people; a farmer named Steven is unable to save his beloved mouse, Molly.

Jodie's celebrity is on the rise and M.O.D.O.K. plans on winning her back from her new boyfriend, the superhero Wonder Man. Jodie and her publicist invite M.O.D.O.K. to a party, knowing his temper will bring publicity. M.O.D.O.K. provokes Wonder Man into attacking him at the party and is kicked out. Wonder Man leaves Jodie when he sees she’s only using him for exposure. Melissa and Lou bond over their disappointment in their parents. M.O.D.O.K. and Jodie have sex when he goes to apologize, and it is revealed who exactly was behind her publicist’s actions.

Oh no! The Red Goobler's back and this time he's jacked! This one's too scary for me.

Without telling Emily or her parents anything, Bill decides with Zoe to test on Emily the biological weapon he hopes to be able to use against the aliens. Catherine, for her part, has had difficulty managing her grief since Mokrani's death. She now has only one thing on her mind: to find out who Bill Ward is and find him. Sophia is ready to help him, but Nathan hesitates.

The fates of a patient in critical condition and a helicopter-bound medical team hang in the balance; Teddy and Owen work on their marriage; Bailey, Blue and Link treat a hospital employee.

Teddy and Owen plan a date night that gets derailed in more ways than one; Jo struggles to do it all at home; Mika adds more to her plate to make up for taking time off to be with her sister; Levi is faced with a monumental decision.

Susan is surprised when she finds out who Edie's new boyfriend is. Meanwhile, Lynette has gone back to work, leaving Tom at home in charge of the house. Carlos makes an unusual request to Gabrielle after his life is threatened behind bars. Lastly, pharmacist George reemerges in Bree's life, which sets off an alarm to mother-in-law Phyllis and her suspicions surrounding her son's death.

Susan tries bravely to accept Edie’s new role in Julie’s life, while Lynette’s demanding boss makes her miss Parker’s first day of kindergarten. Bree later on takes a polygraph test to prove her innocence in Rex's death and realizes she has feelings for George. Gabrielle finally comes to the truth about Carlos and John after seeing John with another woman.

Nic and Conrad contemplate their past when they team up to diagnose a happy husband and wife who are both admitted to the hospital with mysterious symptoms. Bell and Marshall butt heads on a work trip when their cut-throat business tactics don’t align. Meanwhile, AJ turns down a request from Bell despite Mina’s forewarning, Devon continues to gravitate to medical device rep Julian and the staff gears up for Conrad’s three-year anniversary at Chastain.

The fates of a patient in critical condition and a helicopter-bound medical team hang in the balance; Teddy and Owen work on their marriage; Bailey, Blue and Link treat a hospital employee.

Teddy and Owen plan a date night that gets derailed in more ways than one; Jo struggles to do it all at home; Mika adds more to her plate to make up for taking time off to be with her sister; Levi is faced with a monumental decision.

Susan is surprised when she finds out who Edie's new boyfriend is. Meanwhile, Lynette has gone back to work, leaving Tom at home in charge of the house. Carlos makes an unusual request to Gabrielle after his life is threatened behind bars. Lastly, pharmacist George reemerges in Bree's life, which sets off an alarm to mother-in-law Phyllis and her suspicions surrounding her son's death.

Susan tries bravely to accept Edie’s new role in Julie’s life, while Lynette’s demanding boss makes her miss Parker’s first day of kindergarten. Bree later on takes a polygraph test to prove her innocence in Rex's death and realizes she has feelings for George. Gabrielle finally comes to the truth about Carlos and John after seeing John with another woman.

After Max's declaration fractures his relationship with Avery, he leaves the ship and finds himself caught in an earthquake, which triggers a tsunami warning; with The Odyssey forced to leave port, Max races to return before it's too late.

Chastain is flooded with concert goers when a stampede at a music festival grounds leaves many in need of doctors. As Conrad and Nic race to help Josh Robinson, a professional adventure guide with a long list of prior injuries, Devon works with a musician who swears he is sober, even though his toxicology report suggests otherwise. Meanwhile, Bell stirs the pot when the hospital’s revered orthopedic surgeon, Dr. Kit Voss, demands a better resident, Julian works to get her boss on Bell’s good side and Winthrop continues to push Conrad to believe he’s a changed man.

The doctors must put aside their emotions under intense circumstances; Levi asks James a shocking question that could impact their future.

In the midst of a deadly heat wave, the team at Grey Sloan struggles to keep up with an overwhelming amount of patients; Amelia and Winston face a challenging surgery; Jo and Lucas run an errand for the hospital that takes an unexpected turn.

On one of Gabrielle's prison visits to see Carlos she creates a terrible riot, which lands Carlos in hot water. Also, Susan puts her feelings aside and joins Mike in searching for his son Zach. Lynette is surprised to find out that her son Parker has an imaginary friend. Lastly, George and Andrew both vie for Bree's attention as they both compete in making each other look bad in front of her, until one fight goes a little too far.

Susan's longtime book agent and dear friend, Lonny Moon gets into financial trouble. Lynette is forced to go out to bars night after night with her man-hungry boss, Nina. Bree finds out about Rex's feelings about her prior to his death. Lastly, Gabrielle hires hotshot lawyer David Bradley to defend Carlos in court but Carlos rejects him after he witnesses an attraction between David and Gabrielle.

Station 19 and Station 23 each attempt to celebrate Thanksgiving following the fallout from the neighborhood explosion. The firefighters come together to cook, toast to loved ones they have lost, and celebrate the families they have become.

When a car careens out of control over an embankment, killing a middle-aged man in the driver's seat, Megan learns that all is not well on a pretty suburban cul-de-sac.

Megan suspects foul play when a young socialite dies, even though she had a terminal illness. The investigation means the funeral is halted but it doesn't help that the body was embalmed before the autopsy leaving few clues for the team.

After Max's declaration fractures his relationship with Avery, he leaves the ship and finds himself caught in an earthquake, which triggers a tsunami warning; with The Odyssey forced to leave port, Max races to return before it's too late.

A Station 19 firefighter lands in the emergency room for severe burn treatment; the team treats an elderly patient impaled by an art structure.

When a car careens out of control over an embankment, killing a middle-aged man in the driver's seat, Megan learns that all is not well on a pretty suburban cul-de-sac.

After Max's declaration fractures his relationship with Avery, he leaves the ship and finds himself caught in an earthquake, which triggers a tsunami warning; with The Odyssey forced to leave port, Max races to return before it's too late.

Station 19 and Station 23 each attempt to celebrate Thanksgiving following the fallout from the neighborhood explosion. The firefighters come together to cook, toast to loved ones they have lost, and celebrate the families they have become.

On one of Gabrielle's prison visits to see Carlos she creates a terrible riot, which lands Carlos in hot water. Also, Susan puts her feelings aside and joins Mike in searching for his son Zach. Lynette is surprised to find out that her son Parker has an imaginary friend. Lastly, George and Andrew both vie for Bree's attention as they both compete in making each other look bad in front of her, until one fight goes a little too far.

Gabrielle tries to revisit her past when old friends come to town, but doesn't want anyone to know that she's three months pregnant. With the aftermath of her breakup with Mike, Susan finds temporary solace from her ex-husband Karl as his relationship with Edie hits a bump. Also, the Scavos learn more about the new neighbors, the Harpers when they babysit their children and uncover a sex tape of the couple. Lastly, Caleb gets loose from the basement and roams around Wisteria Lane at night, which leads to major consequences for Gabrielle.

The aftermath of the convenience store shooting brings chaos to Grey Sloan; Ben hits a wall with his new emergency preparedness plan; romantic tensions surface for Owen; Amelia and Winston disagree over the surgical plan for a young patient.

Meredith and Nick return to Grey Sloan to treat a liver transplant patient; Bailey hosts an intern retreat at her home; Winston and Ben aid an unexpected crash victim.

When Bell makes the executive call to utilize Julian Booth's medical devices, rather than the hospital's usual products, Kit and AJ must stop their momentary feuding in order to team up against him. Elsewhere in the hospital, Conrad and Nic work to make a child's dreams come true after finding out his cancer has returned and the rest of the staff takes notice of Julian and Devon's new friendship.