The Station 19 crew offers aid to a man who sets himself on fire. Theo proves his devotion to Vic; Sullivan seeks advice from Dr. Webber; and Travis comes to a realization about his love life.

Without telling Emily or her parents anything, Bill decides with Zoe to test on Emily the biological weapon he hopes to be able to use against the aliens. Catherine, for her part, has had difficulty managing her grief since Mokrani's death. She now has only one thing on her mind: to find out who Bill Ward is and find him. Sophia is ready to help him, but Nathan hesitates.

Catherine, Sophia and Nathan make their way to London, accompanied by Victor, a survivor encountered by chance. Along the way, the dangers multiply. Sacha's feelings towards Emily intensify and the young man's behavior becomes more and more disturbing. Feeling threatened, Bill is forced to flee.

Dinner Time! Korvo wins top prize at the annual neighborhood rib festival.

Korvo and Terry place nanobots in the city's water supply to spy on their neighbors. Learning they are not well-liked, Korvo and Terry use the information from the nanobots to win over the community, and run for president of their homeowner association. The nanobots form a sentient person that runs for president as well, and all three expose embarrassing secrets about their neighbors, who break out in violence. The incumbent president Ruth restores order and turns the crowd against Korvo, Terry, and the nanobot person, who escapes from Korvo. Jesse – concerned that Yumyulack is shrinking and capturing too many humans – uses technology to manipulate people who were mean to Yumyulack, hoping to teach him that humans are generally kind.

After getting kicked out of the A-List villains' Soho Lair, M.O.D.O.K. decides to slum it at The Bar With No Name. There, he forms a crew of street-level baddies, intent on using them for a heist that will get him back into the Soho Lair. However, after a wild night of bonding and backstory sharing, they form a real camaraderie. Meanwhile, Jodie goes looking for M.O.D.O.K. at AIM and bonds with Monica while Lou meets Monica's daughter, Carmilla. College-aged M.O.D.O.K. has returned from the time stream and kidnaps the Super Adaptoid.

Bill's latest discovery is put in jeopardy, even as trouble brews with the human aliens; Catherine must decide where her loyalties lie.

A window washer's platform crashes through a hospital window, testing the Grey Sloan team's limits; Blue and Simone clash over their living arrangements; Lucas strives to impress Catherine while on her service.

Amelia undertakes a high-risk brain surgery on a young patient; Winston and Jules disagree over how to handle their trauma patient's family; Jo and Link struggle with wedding planning.

After a number of bad dates, Susan finally meets Dr. Right. Susan flirts with a handsome doctor, but they accidentally head butt. Meanwhile, some old pictures of Gabrielle turn up on the Internet. Tom is alarmed when his kids come down with chicken pox because he never had it. Bree gets arrested. Lastly, after months of silence, Noah Taylor contacts Mike Delfino.

Dr. Ron informs Susan that she needs a splenectomy. Gabrielle and her arch-enemy Sister Mary Bernard finally face off in church. Also, Tom decides to apply for an empty position at Lynette's job, which leads to the arousal of past issues in their marriage. Lastly, Matthew and Danielle's relationship is found out by both their mothers, which leads to big repercussions later on for Bree and her past secret with Andrew last year.

Conrad goes head-to-head with Bell after he recommends one of Julian's risky medical devices to Zoey, who's already lost one son and is back in the hospital with the other. Nic fears that Conrad may be getting overly attached to his patient. Meanwhile, Mina and Austin grow closer while working on a difficult heart transplant, Devon embarks on a very difficult day and Dr. Lane Hunter returns.

A window washer's platform crashes through a hospital window, testing the Grey Sloan team's limits; Blue and Simone clash over their living arrangements; Lucas strives to impress Catherine while on her service.

Amelia undertakes a high-risk brain surgery on a young patient; Winston and Jules disagree over how to handle their trauma patient's family; Jo and Link struggle with wedding planning.

After a number of bad dates, Susan finally meets Dr. Right. Susan flirts with a handsome doctor, but they accidentally head butt. Meanwhile, some old pictures of Gabrielle turn up on the Internet. Tom is alarmed when his kids come down with chicken pox because he never had it. Bree gets arrested. Lastly, after months of silence, Noah Taylor contacts Mike Delfino.

Dr. Ron informs Susan that she needs a splenectomy. Gabrielle and her arch-enemy Sister Mary Bernard finally face off in church. Also, Tom decides to apply for an empty position at Lynette's job, which leads to the arousal of past issues in their marriage. Lastly, Matthew and Danielle's relationship is found out by both their mothers, which leads to big repercussions later on for Bree and her past secret with Andrew last year.

When Max's transmission goes silent, he and Barry seek refuge in an abandoned church while Tristan takes charge of The Odyssey; Avery leads a high-stakes, rescue mission to find Max.

Devon's doubts about his relationship reach a peak as his friends and family gather for his big wedding day. As Chastain's leading medical device company, Quovadis, continues to succeed, Julian (guest star Jenna Dewan) makes a discovery that leaves her uneasy about her involvement in it all. Meanwhile, Conrad continues to work on his relationship with Marshall and Bell takes a risky offer in order to make a mistake from his past disappear.

Jo and Link's wedding day arrives, along with some visitors; Teddy and Owen are met with a familiar face seeking treatment; Lucas disagrees with Simone on how to approach a patient's worsened condition.

The interns are excited to transition to second-year residency; a medical emergency unfolds in the operating room, endangering lives inside the hospital.

Tom tries hard to bond with his new boss and tries to get Lynette to help him out. Meanwhile, Susan gets some help from Edie and Karl on her situation of getting health insurance before her upcoming surgery. Gabrielle becomes very attached to a temporary Chinese immigrant housekeeper who is staying with Solis' after being rescued by another slave owner employer. Lastly, Bree tries to uncover more about the Applewhites by sneaking into their house to meet Caleb.

Edie thinks that Karl is going to pop the question after she finds an engagement ring and prenuptial agreement in his briefcase. Also, Gabrielle and Carlos learn she is highly unable to conceive a child again because of complications caused from her recent miscarriage. Lastly, Bree's problem with alcohol intensifies with the notice of Lynette after Bree babysits her children.

The Station 19 crew offers aid to a man who sets himself on fire. Theo proves his devotion to Vic; Sullivan seeks advice from Dr. Webber; and Travis comes to a realization about his love life.

A champion equestrian is killed and potential drug use is suspected, but when Megan's daughter, who also rides, overhears details of the case, she leads the team to a clue and possibly the murderer.

Peter stumbles upon a house fire in progress before the fire department arrives and is able to rescue a young woman. When Megan goes to the scene of the fire, she discovers that there is another victim who perished in the fire.

When Max's transmission goes silent, he and Barry seek refuge in an abandoned church while Tristan takes charge of The Odyssey; Avery leads a high-stakes, rescue mission to find Max.

After a catastrophic bridge collapse sends dozens of victims to Grey Sloan, the hospital activates its full disaster response as they race to treat a surge of critically injured patients.

A champion equestrian is killed and potential drug use is suspected, but when Megan's daughter, who also rides, overhears details of the case, she leads the team to a clue and possibly the murderer.

When Max's transmission goes silent, he and Barry seek refuge in an abandoned church while Tristan takes charge of The Odyssey; Avery leads a high-stakes, rescue mission to find Max.

The Station 19 crew offers aid to a man who sets himself on fire. Theo proves his devotion to Vic; Sullivan seeks advice from Dr. Webber; and Travis comes to a realization about his love life.

Tom tries hard to bond with his new boss and tries to get Lynette to help him out. Meanwhile, Susan gets some help from Edie and Karl on her situation of getting health insurance before her upcoming surgery. Gabrielle becomes very attached to a temporary Chinese immigrant housekeeper who is staying with Solis' after being rescued by another slave owner employer. Lastly, Bree tries to uncover more about the Applewhites by sneaking into their house to meet Caleb.

Susan invites Dr. Ron to meet Karl after he finds out about their arranged marriage. Lynette is surprised that a woman at work is still breastfeeding her child of five. Gabrielle becomes very picky when choosing a birth mother, and a beautiful baby. Bree has to deal with a fresh accusation from Andrew, that of repressed memories.

After the catastrophic hospital explosion, Grey Sloan's staff scrambles to save not only their patients' lives but also their own; confronted with impossible surgical decisions and emotional turmoil, they fight to preserve life amid devastation.

The team at Grey Sloan navigates a chaotic first day of surgical rotations amid hospital renovations; Meredith spends time with Amelia.

Lane Hunter's victims and their families become outraged when she is released from prison. Bell, although responsible for posting Lane's bail and getting her released, continues to be tortured by her manipulation.